Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethyl Hydrogen Phosphate SCHEMBL28772823 | 0.87 | NOS3 (0.52) | TSHRPPARDTDP1 | |
| Diethyl Hydrogen Phosphate SCHEMBL27873282 | 0.83 | PPARD (0.38) | TSHRPPARDTP53TDP1ALOX15 | |
| Diethyl Hydrogen Phosphate SCHEMBL93056 | 0.83 | — | — | |
| Diethyl Hydrogen Phosphate SCHEMBL27294237 | 0.83 | TSHR (0.56) | TSHRPPARDTP53TDP1CA12 | |
| Diethyl Hydrogen Phosphate SCHEMBL11752938 | 0.80 | TSHR (0.53) | TSHRPPARDTP53TDP1CA12 | |
| Diethyl Hydrogen Phosphate SCHEMBL906759 | 0.80 | TSHR (0.53) | TSHRPPARDTP53TDP1CA12 | |
| Diethyl Hydrogen Phosphate SCHEMBL11757040 | 0.80 | TSHR (0.53) | TSHRPPARDTP53TDP1CA12 | |
| Diethyl Hydrogen Phosphate SCHEMBL3133022 | 0.80 | TSHR (0.53) | TSHRPPARDTP53TDP1CA12 | |
| Diethyl Hydrogen Phosphate SCHEMBL4948463 | 0.80 | TSHR (0.53) | TSHRPPARDTP53TDP1CA12 | |
| Diethyl Hydrogen Phosphate SCHEMBL6694735 | 0.80 | TSHR (0.53) | TSHRPPARDTP53TDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101917848-B | S-alkylisothiouronium derivatives for the treatment of uterine hypercontractility disorders | BARKAN FARMA S R L | 2014-02-12 | — | — | CN | claimed |
| CN-101917848-A | S-alkylisothiouronium derivatives for the treatment of uterine hypercontractility disorders | BARKAN FARMA S R L | 2010-12-15 | — | — | CN | claimed |
| CN-101300003-A | Prevention of hypotension and stabilization of blood pressure in hemodialysis patients | MEDITOR PHARMACEUTICALS LTD (IL) | 2008-11-05 | — | — | CN | claimed |
| CN-1116871-C | Pharmaceutical compositions containing S-alkylisothiouronium derivatives | MEDITOR PHARMACEUTICALS LTD (IL) | 2003-08-06 | — | — | CN | claimed |
| CN-1234737-A | Pharmaceutical compositions containing S-alkylisothiouronium derivatives | MEDITOR PHARMACEUTICALS LTD (IL) | 1999-11-10 | — | — | CN | claimed |
| CN-101917848-B | S-alkylisothiouronium derivatives for the treatment of uterine hypercontractility disorders | BARKAN FARMA S R L | 2014-02-12 | — | — | CN | disclosed |
| CN-101917848-A | S-alkylisothiouronium derivatives for the treatment of uterine hypercontractility disorders | BARKAN FARMA S R L | 2010-12-15 | — | — | CN | disclosed |
| CN-101300003-A | Prevention of hypotension and stabilization of blood pressure in hemodialysis patients | MEDITOR PHARMACEUTICALS LTD (IL) | 2008-11-05 | — | — | CN | disclosed |
| CN-1116871-C | Pharmaceutical compositions containing S-alkylisothiouronium derivatives | MEDITOR PHARMACEUTICALS LTD (IL) | 2003-08-06 | — | — | CN | disclosed |
| CN-1234737-A | Pharmaceutical compositions containing S-alkylisothiouronium derivatives | MEDITOR PHARMACEUTICALS LTD (IL) | 1999-11-10 | — | — | CN | disclosed |
| EP-0928191-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING S-ALKYLISOTHIOURONIUM DERIVATIVES | Meditor Pharmaceuticals Ltd. (IL) | 1999-07-14 | — | — | EP | disclosed |
| WO-1998013036-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING S-ALKYLISOTHIOURONIUM DERIVATIVES | MEDITOR PHARMACEUTICALS LTD. (IL) | 1998-04-02 | — | — | WO | disclosed |