Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 3/20 | 0.49 |
| ▸ | FLT1 | P17948 | 4/20 | 0.47 |
| ▸ | FLT4 | P35916 | 4/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408910 | 0.89 | MEN1 (0.44) | KMT2AMEN1GAAPKMFLT1 | |
| SCHEMBL1471557 | 0.87 | THRA (0.55) | KMT2AMEN1GAAPKMTHRA | |
| SCHEMBL1471384 | 0.85 | KMT2A (0.50) | KMT2AMEN1GAAPKMTHRA | |
| SCHEMBL1471382 | 0.85 | KMT2A (0.50) | KMT2AMEN1GAAPKMTHRA | |
| SCHEMBL1471229 | 0.83 | CYP2C9 (0.53) | KMT2AMEN1GAAPKMTHRA | |
| SCHEMBL1473874 | 0.81 | THRA (0.59) | KMT2AMEN1GAAPKMTHRA | |
| SCHEMBL1471950 | 0.79 | KMT2A (0.53) | KMT2AMEN1GAAPKMTHRA | |
| SCHEMBL1471953 | 0.79 | KMT2A (0.53) | KMT2AMEN1GAAPKMTHRA | |
| SCHEMBL13485840 | 0.78 | THRA (0.59) | KMT2AMEN1GAAPKMTHRA | |
| SCHEMBL1471523 | 0.78 | THRA (0.51) | KMT2AMEN1GAAPKMTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942546-A | Sulfonyl-N-hydroxyguanidine derivatives | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 1999-08-24 | — | — | US | disclosed |