Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410932 | 0.88 | PTGIR (0.61) | PTGIRKDM4CTBXAS1 | |
| SCHEMBL8808532 | 0.84 | PTGIR (0.46) | PTGIRKDM4CSIGMAR1TBXAS1 | |
| SCHEMBL8808893 | 0.82 | PTGIR (0.36) | PTGIRKDM4C | |
| SCHEMBL8413677 | 0.77 | PTGIR (0.46) | PTGIRKDM4CSIGMAR1TBXAS1 | |
| SCHEMBL8812584 | 0.77 | MEN1 (0.36) | PTGIRSIGMAR1 | |
| SCHEMBL8813595 | 0.76 | PTGIR (0.45) | PTGIRKDM4CSIGMAR1TBXAS1 | |
| SCHEMBL8808475 | 0.76 | PTGIR (0.47) | PTGIRSIGMAR1 | |
| SCHEMBL8411072 | 0.76 | PTGIR (0.78) | PTGIRSIGMAR1 | |
| SCHEMBL8808959 | 0.75 | PTGIR (0.47) | PTGIRSIGMAR1 | |
| SCHEMBL8520475 | 0.74 | PTGIR (0.70) | PTGIRKDM4CSIGMAR1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | claimed |
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |