Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RBP1 | P09455 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808532 | 0.92 | PTGIR (0.46) | PTGIRPKMPOLBNPSR1RBP1 | |
| SCHEMBL8413677 | 0.87 | PTGIR (0.46) | PTGIRPKMPOLBNPSR1RBP1 | |
| SCHEMBL8574945 | 0.86 | PTGIR (0.61) | PTGIRPKMPOLBKDM4CTBXAS1 | |
| SCHEMBL8413675 | 0.85 | PTGIR (0.51) | PTGIRPKMPOLBNPSR1RBP1 | |
| SCHEMBL8410934 | 0.76 | PTGIR (0.46) | PTGIRSIGMAR1KDM4CTBXAS1 | |
| SCHEMBL8808958 | 0.76 | PTGIR (0.46) | PTGIRSIGMAR1 | |
| SCHEMBL8809390 | 0.74 | PTGIR (0.47) | PTGIRSIGMAR1 | |
| SCHEMBL8808618 | 0.74 | PTGIR (0.48) | PTGIRSIGMAR1 | |
| SCHEMBL8811203 | 0.73 | PTGIR (0.42) | PTGIRSIGMAR1 | |
| SCHEMBL8811966 | 0.71 | PTGIR (0.49) | PTGIRSIGMAR1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5589496-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor agonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |