SCHEMBL8411037

SCHEMBL8411037

O=C[C@@H]1CC[C@@H]2OC(=O)C[C@H]12

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8947855 1.00 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL8947849 1.00 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL13595438 1.00 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL8947846 1.00 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL11459579 1.00 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL10047143 1.00 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL18388406 0.82 PRSS1 (0.38) SMN1; SMN2
SCHEMBL9471099 0.82 SMN1; SMN2 (0.34) SMN1; SMN2
SCHEMBL14729803 0.78 — —
SCHEMBL12808379 0.73 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0690049-B1 Agent for treating hepato biliary diseases R TECH UENO LTD (JP) 1999-08-04 — — EP disclosed
EP-0690049-A2 Agent for treating hepato biliary diseases R-TECH UENO LTD. (JP) 1996-01-03 — — EP disclosed
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