Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947855 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL13595438 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL8411037 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL8947846 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL11459579 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL10047143 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL18388406 | 0.82 | PRSS1 (0.38) | SMN1; SMN2 | |
| SCHEMBL9471099 | 0.82 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL14729803 | 0.78 | — | — | |
| SCHEMBL12808379 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-5486540-A | Cyclopentane heptanoic or heptenoic acid, 2-arylalkyl or arylalkenyl and derivatives as therapeutic agents | ALLERGAN, INC. (US) | 1996-01-23 | — | — | US | disclosed |
| US-4596823-A | Prostaglandins | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-06-24 | — | — | US | disclosed |
| EP-0043292-B1 | PROSTAGLANDINS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-01-15 | — | — | EP | disclosed |
| US-4410720-A | HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1983-10-18 | — | — | US | disclosed |
| US-4256911-A | TRIFLUOROMETHYL-CARBOXY ESTERS | HOFFMANN-LA ROCHE INC. (US) | 1981-03-17 | — | — | US | disclosed |
| US-4246426-A | USEFUL IN INDUCING LABOR, TERMINATING PREGNANCY, TREATING GASTRIC HYPERACIDITY, WITH CARDIOVASCULAR AND BRONCHODILATOR EFFECTS | HOFFMANN-LA ROCHE INC. (US) | 1981-01-20 | — | — | US | disclosed |
| US-4246402-A | CARDIOVASCULAR AGENTS AND OXYTOCICS | HOFFMANN-LA ROCHE INC. (US) | 1981-01-20 | — | — | US | disclosed |
| US-4237276-A | CARDIOVASCULAR AGENTS, INDUCTION OF LABOR, TERMINATION OF PREGNANCY | HOFFMANN-LA ROCHE INC. (US) | 1980-12-02 | — | — | US | disclosed |
| US-4227019-A | CARDIOTONIC AGENTS; OXYTOCICS | HOFFMANN-LA ROCHE INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4211724-A | ENANTIOMORPHS, INTERMEDIATE AMIDES WITH ASSYMETRIC CARBON ATOM | HOFFMAN-LA ROCHE INC. (US) | 1980-07-08 | — | — | US | disclosed |
| US-4190587-A | PROSTAGLANDINS | HOFFMANN-LA ROCHE INC. (US) | 1980-02-26 | — | — | US | disclosed |
| US-4187381-A | CARDIOVASCULAR AGENTS; OXYTOCICS | HOFFMANN-LA ROCHE INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-4130721-A | 11-Deoxy PGE2 compounds | THE UPJOHN COMPANY (US) | 1978-12-19 | — | — | US | disclosed |
| US-4112225-A | 16-CF3 prostaglandins | HOFFMAN-LA ROCHE INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4059576-A | CARDIOVASCULAR, OXYTOCICS | HOFFMANN-LA ROCHE, INC. (US) | 1977-11-22 | — | — | US | disclosed |
| US-4052446-A | OXYTOCICS, CARDIOVASCULAR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1977-10-04 | — | — | US | disclosed |
| US-3931279-A | 5-Oxa prostaglandin F2.sub.α analogs | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |