SCHEMBL8411175

SCHEMBL8411175

CCCCC(C#N)C[Si](Cl)(Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
FDPS P14324 1/20 0.31
DNM1 Q05193 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8413567 0.94 TSHR (0.36) TSHRFDPSDNM1
SCHEMBL8411253 0.92 FDPS (0.35) TSHRFDPSDNM1
SCHEMBL8414390 0.89
SCHEMBL8407184 0.79
SCHEMBL3677002 0.78 TSHR (0.50) TSHRFDPSDNM1
SCHEMBL10155552 0.74 TSHR (0.46) TSHRFDPSDNM1
SCHEMBL3671291 0.74
SCHEMBL3673710 0.74 TSHR (0.46) TSHRFDPSDNM1
SCHEMBL27666685 0.73 TSHR (0.40) TSHRDNM1
SCHEMBL27685595 0.73 TSHR (0.46) TSHRDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0654475-B1 Catalytic preparation of beta-cyanoalkylsilane DOW CORNING (US) 1999-08-11 EP disclosed
EP-0605225-B1 Process for preparation of beta-cyanoalkylsilanes DOW CORNING (US) 1997-11-19 EP disclosed
EP-0654475-A1 Catalytic preparation of beta-cyanoalkylsilane DOW CORNING CORPORATION (US) 1995-05-24 EP disclosed
US-5374756-A Addition of trihalosilane to alpha-beta unsaturated olefinic nitriles DOW CORNING CORPORATION (US) 1994-12-20 US disclosed
US-5359107-A β-cyanoalkylsilane preparation using triorganophosphine compounds as catalyst DOW CORNING CORPORATION (US) 1994-10-25 US disclosed
US-5332848-A From unsaturated nitrile and trihalosilane DOW CORNING CORPORATION (US) 1994-07-26 US disclosed
EP-0605225-A1 Process for preparation of beta-cyanoalkylsilanes DOW CORNING CORPORATION (US) 1994-07-06 EP disclosed
US-5326894-A β-cyanoalkylsilane preparation using divinylbenzene/4-vinylpyridine copolymer resin as catalyst DOW CORNING CORPORATION (US) 1994-07-05 US disclosed
US-5262554-A Hydrosilylation, supported aminosilane catalyst DOW CORNING CORPORATION (US) 1993-11-16 US disclosed
US-5247109-A Aminosilane catalyst DOW CORNING CORPORATION (US) 1993-09-21 US disclosed