SCHEMBL8411191

SCHEMBL8411191

O=C=Nc1cc(-c2ccccc2)c(N=C=O)c(N=C=O)c1N=C=O

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.37
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
BACE1 P56817 2/20 0.33
TRPA1 O75762 1/20 0.33
CASP3 P42574 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10734575 0.86 CYP3A4 (0.35) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL6752522 0.84 CYP3A4 (0.38) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL4615756 0.81 CYP3A4 (0.46) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL28909456 0.78 GABRA1 (0.37) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL11204983 0.78 CYP3A4 (0.43) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL10734571 0.77 CYP3A4 (0.38) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL113386 0.76 CYP3A4 (0.47) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL3981805 0.76 CYP3A4 (0.39) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL10454805 0.76 CYP3A4 (0.41) CYP3A4GABRA1GABRB2ALDH1A1HPGD
Methane SCHEMBL27978530 0.75 CYP3A4 (0.46) CYP3A4GABRA1GABRB2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0930379-A1 Method of chemical conversion coating for low-lead electrodeposition coating Nippon Paint Co., Ltd. (JP) 1999-07-21 EP disclosed
US-5055168-A Containing mixture of crosslinking agents BASF LACKE + FARBEN AKTIENGESELLSCHAFT (DE) 1991-10-08 US disclosed