Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MMP8 | P22894 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411454 | 1.00 | KMT2A (0.54) | KMT2AMMP8EGFRGAAMME | |
| SCHEMBL8412726 | 1.00 | KMT2A (0.54) | KMT2AMMP8EGFRGAAMME | |
| SCHEMBL27449719 | 0.84 | KMT2A (0.53) | KMT2AMMP8EGFRGAAMME | |
| SCHEMBL6284583 | 0.84 | CYP2D6 (0.56) | KMT2AMMP8EGFRGAAMME | |
| SCHEMBL20407732 | 0.84 | KMT2A (0.57) | KMT2AMMP8GAAMMEALDH1A1 | |
| SCHEMBL9617186 | 0.84 | MMP8 (0.53) | KMT2AMMP8EGFRGAAMME | |
| SCHEMBL17548796 | 0.84 | KMT2A (0.57) | KMT2AMMP8GAAMMEALDH1A1 | |
| SCHEMBL9276848 | 0.84 | KMT2A (0.57) | KMT2AMMP8GAAMMEALDH1A1 | |
| SCHEMBL714386 | 0.82 | KMT2A (0.59) | KMT2AMMP8GAAMMECYP2D6 | |
| SCHEMBL6522964 | 0.82 | KMT2A (0.59) | KMT2AMMP8GAAMMECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880158-A | TREATMENT OF EPILEPSY AND OTHER CENTRAL NERVOUS SYSTEM DISORDERS | RESEARCH CORPORATION TECH., INC. (US) | 1999-03-09 | — | — | US | disclosed |
| WO-1998013336-A1 | PROPIONAMIDE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-04-02 | — | — | WO | disclosed |