Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3041972 | 0.81 | TSHR (0.41) | TSHREPHX1CES1SRCKMT2A | |
| SCHEMBL210844 | 0.81 | TSHR (0.41) | TSHREPHX1CES1SRCKMT2A | |
| SCHEMBL3643052 | 0.80 | TSHR (0.40) | TSHREPHX1CES1SRCKMT2A | |
| SCHEMBL2470208 | 0.79 | EPHX1 (0.43) | TSHREPHX1CES1KMT2AMEN1 | |
| SCHEMBL8488412 | 0.78 | CES1 (0.35) | TSHREPHX1CES1KMT2AMEN1 | |
| SCHEMBL10583727 | 0.78 | TSHR (0.39) | TSHREPHX1CES1SRCKMT2A | |
| SCHEMBL8574301 | 0.78 | TSHR (0.39) | TSHREPHX1CES1SRCKMT2A | |
| SCHEMBL7400357 | 0.77 | TSHR (0.38) | TSHREPHX1CES1SRCKMT2A | |
| SCHEMBL5190188 | 0.77 | TSHR (0.38) | TSHREPHX1CES1SRCKMT2A | |
| SCHEMBL10705123 | 0.76 | EPHX1 (0.39) | TSHREPHX1CES1SRCKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934247-A1 | PHOTOINITIATORS | Lambson Fine Chemicals Limited (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997049664-A1 | PHOTOINITIATORS | LAMBSON FINE CHEMICALS LIMITED (GB) | 1997-12-31 | — | — | WO | disclosed |