SCHEMBL210844

SCHEMBL210844

COC1(OC)C=CC(C(=O)c2ccccc2)C=C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
EPHX1 P07099 3/20 0.40
CES1 P23141 2/20 0.39
SRC P12931 1/20 0.39
HTT P42858 2/20 0.37
ALOX15 P16050 2/20 0.37
CES2 O00748 1/20 0.37
MAPT P10636 1/20 0.37
HBB P68871 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36
ALDH1A1 P00352 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
GAA P10253 1/20 0.36
F2 P00734 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3041972 0.86 TSHR (0.41) TSHREPHX1CES1SRCHTT
SCHEMBL3643052 0.85 TSHR (0.40) TSHREPHX1CES1SRCHTT
SCHEMBL2470208 0.84 EPHX1 (0.43) TSHREPHX1CES1HTTALOX15
SCHEMBL10586101 0.83 ELANE (0.38) TSHREPHX1CES1SRCHTT
SCHEMBL10583727 0.83 TSHR (0.39) TSHREPHX1CES1SRCHTT
SCHEMBL8574301 0.83 TSHR (0.39) TSHREPHX1CES1SRCHTT
SCHEMBL5190188 0.82 TSHR (0.38) TSHREPHX1CES1SRCHTT
SCHEMBL8911079 0.81 HTT (0.36) TSHREPHX1CES1HTTALOX15
SCHEMBL10705123 0.81 EPHX1 (0.39) TSHREPHX1CES1SRCHTT
SCHEMBL8411550 0.81 TSHR (0.37) TSHREPHX1CES1SRCHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114479735-A Cationic UV curing adhesive and preparation method and application thereof 张河远 2022-05-13 CN claimed
CN-107123467-B A kind of flexible conductive film and its application 张家港康得新光电材料有限公司 2019-06-21 CN claimed
CN-109439035-A A kind of environmentally friendly ceramic film coating of exterior wall 常州天瑞新材料科技有限公司 2019-03-08 CN claimed
EP-2574638-B1 (Meth)acrylic-Modified Organopolysiloxane, Radiation-Curable Silicone Composition, Silicone Release Liner, and Making Methods SHINETSU CHEMICAL CO (JP) 2017-09-06 EP claimed
CN-106147585-A High ferro Special high-strength water-repellent paint 王斐芬 2016-11-23 CN claimed
CN-103756383-B Cured film Antiblock coating composition and corresponding two-sided cured film 张家港康得新光电材料有限公司 2016-09-07 CN claimed
EP-1995260-B1 HIGH ENERGY RAY-CURABLE COMPOSITION DOW CORNING (US) 2016-07-20 EP claimed
US-8791170-B2 Photocurable organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-07-29 US claimed
CN-103756383-A Anti-adhesion coating composition used for hard coating and corresponding double-sided hard coating ZHANGJIAGANG KANGDE XIN PHOTOELECTRIC MATERIAL CO LTD 2014-04-30 CN claimed
US-8609742-B2 High energy ray-curable composition DAIKIN INDUSTRIES, LTD. (JP) 2013-12-17 US claimed
US-6248803-B1 ACRYLATED POLYSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-06-19 US claimed
EP-0514817-B1 Manufacturing method of urethane foam molded products NHK SPRING CO LTD (JP) 1996-09-25 EP claimed
US-5371116-A Long self life SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-12-06 US claimed
EP-0429688-A1 Process for preparing articles of crystallized poly(etheretherketone)-type polymers and the articles prepared thereby THE DOW CHEMICAL COMPANY (US) 1991-06-05 EP claimed
US-12448487-B2 Polysiloxanes with radiation- and moisture-cross-linkable groups WACKER CHEMIE AG (DE) 2025-10-21 US disclosed
WO-2025045467-A1 METHOD FOR DECOMPOSING SULFUR HEXAFLUORIDE UNIVERSITÄT INNSBRUCK (AT) 2025-03-06 WO disclosed
EP-3831868-B1 CURABLE WHITE SILICONE FORMULATION, A REFLECTIVE MATERIAL FOR OPTICAL SEMICONDUCTOR MODULE AND OPTICAL SEMICONDUCTOR DEVICE DUPONT TORAY SPECIALTY MATERIALS KK (JP) 2025-01-08 EP disclosed
WO-1980000844-A1 PHOTOPOLYMERIZED HYDROPHILIC INTERPOLYMERS OF UNSATURATED CARBOXYLIC ACID AND ESTERS GOODRICH CO B F (US) 1980-05-01 WO disclosed
US-4167464-A Photopolymerized hydrophilic interpolymers of unsaturated carboxylic acid and esters THE B. F. GOODRICH COMPANY (US) 1979-09-11 US disclosed
US-4046577-A PHOTOREACTIVE COMPOSITIONS COMPRISING POLYMERS CONTAINING ALKOXYAROMATIC GLYOXY GROUPS THE RICHARDSON COMPANY (US) 1977-09-06 US disclosed