Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Petunidin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 11/20 | 0.95 |
| ▸ | DPP4 | P27487 | 3/20 | 0.90 |
| ▸ | MAOA | P21397 | 2/20 | 0.90 |
| ▸ | GLO1 | Q04760 | 5/20 | 0.78 |
| ▸ | SNCA | P37840 | 3/20 | 0.78 |
| ▸ | EGFR | P00533 | 2/20 | 0.78 |
| ▸ | KDR | P35968 | 2/20 | 0.78 |
| ▸ | EP300 | Q09472 | 2/20 | 0.78 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Petunidin SCHEMBL21649 | 0.99 | CD38 (0.97) | CD38DPP4MAOAGLO1SNCA | |
| Petunidin SCHEMBL29947229 | 0.99 | CD38 (0.97) | CD38DPP4MAOAGLO1SNCA | |
| Petunidin SCHEMBL30683343 | 0.99 | CD38 (0.97) | CD38DPP4MAOAGLO1SNCA | |
| Petunidin SCHEMBL9120043 | 0.97 | CD38 (0.95) | CD38DPP4MAOAGLO1SNCA | |
| Petunidin SCHEMBL30884156 | 0.97 | CD38 (1.00) | CD38DPP4MAOAGLO1SNCA | |
| Petunidin SCHEMBL29372982 | 0.97 | CD38 (1.00) | CD38DPP4MAOAGLO1SNCA | |
| Petunidin SCHEMBL21650 | 0.97 | CD38 (1.00) | CD38DPP4MAOAGLO1SNCA | |
| Malvidin SCHEMBL29640416 | 0.94 | DPP4 (1.00) | CD38DPP4MAOAGLO1SNCA | |
| Malvidin SCHEMBL30683334 | 0.94 | DPP4 (1.00) | CD38DPP4MAOAGLO1SNCA | |
| Malvidin SCHEMBL308690 | 0.94 | DPP4 (1.00) | CD38DPP4MAOAGLO1SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859334-A | FLAVONOID GLYCOSYLATING ENZYMES AND THEIR USE IN MANIPULATING PRODUCTION OF PIGMENTORY MOLECULES IN PLANTS | INTERNATIONAL FLOWER DEVELOPMENTS PTY. LTD. (AU) | 1999-01-12 | — | — | US | disclosed |