SCHEMBL8412657

SCHEMBL8412657

CCOCCOCCOCCOCCOCC[O]

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TSHR P16473 2/20 0.46
THRB P10828 1/20 0.39
CYP3A4 P08684 1/20 0.32
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3926217 1.00 ALDH1A1 (0.46) ALDH1A1TSHRTHRBCYP3A4EPHX2
SCHEMBL37685 1.00
SCHEMBL3169681 1.00 ALDH1A1 (0.46) ALDH1A1TSHRTHRBCYP3A4EPHX2
SCHEMBL4685 0.94
SCHEMBL28499142 0.92 TSHR (0.41) ALDH1A1TSHRTHRBCYP3A4EPHX2
SCHEMBL4394021 0.88 ALDH1A1 (0.39) ALDH1A1TSHRTHRBCYP3A4EPHX2
SCHEMBL3581454 0.88 ALDH1A1 (0.39) ALDH1A1TSHRTHRBCYP3A4EPHX2
SCHEMBL5250530 0.86 ALDH1A1 (0.36) ALDH1A1TSHRTHRB
SCHEMBL987828 0.83 ALDH1A1 (0.56) ALDH1A1TSHRTHRBCYP3A4EPHX2
SCHEMBL5839297 0.83 ALDH1A1 (0.56) ALDH1A1TSHRTHRBCYP3A4EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0751983-B1 LUBRICATING COMPOSITIONS EXXON CHEMICAL LTD (GB) 1999-07-28 EP disclosed
EP-0751983-A1 LUBRICATING COMPOSITIONS EXXON CHEMICAL LIMITED (GB) 1997-01-08 EP disclosed
US-5558805-A OILS CONTAINING SOLUBLE COPPER COMPOUNDS AND HETEROCYCLIC DIAMINE (POLY)SULFIDES AS ADDITIVES EXXON CHEMICAL PATENTS INC (US) 1996-09-24 US disclosed
WO-1995025781-A1 LUBRICATING COMPOSITIONS EXXON CHEMICAL LIMITED (GB) 1995-09-28 WO disclosed
EP-0076784-B1 LUBRICANT COMPOSITIONS AND LUBRICANT ADDITIVES CIBA-GEIGY AG (CH) 1987-08-05 EP disclosed
US-4482463-A EXTREME PRESSURE LUBRICANTS CIBA-GEIGY CORPORATION (US) 1984-11-13 US disclosed
EP-0076784-A2 Lubricant compositions and lubricant additives CIBA-GEIGY AG (CH) 1983-04-13 EP disclosed