Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.53 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29113946 | 0.87 | UBE2T (0.56) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL8414136 | 0.83 | UBE2T (0.56) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL19372016 | 0.80 | UBE2T (0.70) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL22117314 | 0.80 | HPGD (0.51) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL14131194 | 0.80 | UBE2T (0.56) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL2904753 | 0.78 | SMN1; SMN2 (0.51) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL10576351 | 0.78 | UBE2T (0.61) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL8904885 | 0.78 | UBE2T (0.61) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL9641726 | 0.77 | SMN1; SMN2 (0.70) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL1730426 | 0.77 | KDM4E (0.51) | UBE2TASIC3SMN1; SMN2HTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859030-A | Substituted arylalkylthioalkylthiopyridines for use in the control of helicobacter bacteria | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-01-12 | — | — | US | disclosed |
| EP-0764161-A1 | SUBSTITUTED ARYLALKYLTHIOALKYLTHIOPYRIDINES FOR USE IN THE CONTROL OF HELICOBACTER BACTERIA | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995034554-A1 | SUBSTITUTED ARYLALKYLTHIOALKYLTHIOPYRIDINES FOR USE IN THE CONTROL OF HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1995-12-21 | — | — | WO | disclosed |