Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11490094 | 0.87 | MEN1 (0.53) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL11053483 | 0.83 | MEN1 (0.51) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL15135859 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL8412767 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL11210247 | 0.81 | MEN1 (0.50) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL9064055 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL4219708 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL1770114 | 0.79 | GSK3B (0.48) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL5885909 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL4320007 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPTMAPK1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274234-B1 | SPIRO-SUBSITUTED GLUTARAMIDE DIURETIC AGENTS | Pfizer Limited (GB) | 1991-09-11 | — | — | EP | claimed |
| EP-0627476-B1 | PHOTOPOLYMERIZATION INITIATOR COMPOSITION FOR VISIBLE RAY POLYMERIZABLE ADHESIVE | ADELL CO LTD (JP) | 1999-08-04 | — | — | EP | disclosed |
| EP-0627476-A1 | PHOTOPOLYMERIZATION INITIATOR COMPOSITION FOR VISIBLE RAY POLYMERIZABLE ADHESIVE | ADELL CO., LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |