Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.60 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7090686 | 0.75 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL6223221 | 0.72 | KDM4E (0.64) | KDM4EPKMKDM1A | |
| SCHEMBL6223223 | 0.72 | KDM4E (0.64) | KDM4EPKMKDM1A | |
| SCHEMBL2689602 | 0.69 | KLK7 (0.49) | MEN1KMT2AKDM1ANPC1 | |
| SCHEMBL3046705 | 0.69 | KLK7 (0.49) | MEN1KMT2AKDM1ANPC1 | |
| SCHEMBL13086596 | 0.69 | KLK7 (0.49) | MEN1KMT2AKDM1ANPC1 | |
| SCHEMBL4664834 | 0.69 | KDM4E (0.65) | KDM4EPKMKDM1A | |
| Benzoyl Chloride SCHEMBL7166401 | 0.68 | KDM4E (0.58) | KDM4EPKMKDM1A | |
| SCHEMBL6307951 | 0.67 | ANO1 (0.43) | MEN1KMT2AHSD11B1NPC1 | |
| SCHEMBL22652855 | 0.67 | ATM (0.45) | KDM1ACHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |