Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 2/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.55 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.55 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.55 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11506862 | 0.96 | DGKA (0.63) | DGKAFFAR1FFAR4LPAR1LPAR4 | |
| SCHEMBL18968293 | 0.92 | DGKA (0.62) | DGKAFFAR1FFAR4LPAR1LPAR4 | |
| SCHEMBL18968294 | 0.92 | DGKA (0.62) | DGKAFFAR1FFAR4LPAR1LPAR4 | |
| SCHEMBL18968401 | 0.92 | DGKA (0.62) | DGKAFFAR1FFAR4LPAR1LPAR4 | |
| SCHEMBL18969548 | 0.92 | DGKA (0.62) | DGKAFFAR1FFAR4LPAR1LPAR4 | |
| SCHEMBL25340998 | 0.91 | FFAR1 (0.69) | DGKAFFAR1FFAR4LPAR1LPAR4 | |
| SCHEMBL3960493 | 0.91 | FFAR1 (0.69) | DGKAFFAR1FFAR4LPAR1LPAR4 | |
| SCHEMBL1278170 | 0.91 | FFAR1 (0.69) | DGKAFFAR1FFAR4LPAR1LPAR4 | |
| SCHEMBL3657211 | 0.91 | FFAR1 (0.69) | DGKAFFAR1FFAR4LPAR1LPAR4 | |
| SCHEMBL3659434 | 0.91 | FFAR1 (0.69) | DGKAFFAR1FFAR4LPAR1LPAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5959145-A | 12-(METHOXY)DODECANOIC ACID. | WASHINGTON UNIVERSITY (US) | 1999-09-28 | — | — | US | disclosed |
| US-5871954-A | ACYLATION OF PEPTIDE OR PROTEIN BY REACTING WITH COENZYME A ESTER OF AN OXY- OR THIO-SUBSTITUTED FATTY ACID ANALOG IN PRESENCE OF N-MYRISTOYL TRANSFERASE | WASHINGTON UNIVERSITY (US) | 1999-02-16 | — | — | US | disclosed |
| EP-0415902-B1 | OXY- OR THIO-SUBSTITUTED FATTY ACID ANALOGS FOR USE IN THE TREATMENT OF RETROVIRAL INFECTIONS | WASHINGTON UNIVERSITY (US) | 1993-03-17 | — | — | EP | disclosed |
| EP-0327523-B1 | NOVEL FATTY ACID ANALOG ENZYME SUBSTRATES | WASHINGTON UNIVERSITY (US) | 1992-06-17 | — | — | EP | disclosed |
| US-5073571-A | Oxy or thio substituted fatty acid or ester | WASHINGTON UNIVERSITY (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0327523-A1 | Novel fatty acid analog enzyme substrates | WASHINGTON UNIVERSITY (US) | 1989-08-09 | — | — | EP | disclosed |