SCHEMBL8413380

SCHEMBL8413380

CCCCCCCCCCCCC(O)C1CCCCC1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.47
KDM4E B2RXH2 1/20 0.45
GMNN O75496 1/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2858662 1.00 TP53 (0.47) TP53KDM4EGMNNLMNAMAPT
SCHEMBL11607011 1.00 TP53 (0.47) TP53KDM4EGMNNLMNAMAPT
SCHEMBL31562869 1.00 TP53 (0.47) TP53KDM4EGMNNLMNAMAPT
SCHEMBL3427003 0.98 TP53 (0.43) TP53KDM4EGMNNLMNAMAPT
SCHEMBL4535941 0.98 TP53 (0.48) TP53KDM4EGMNNLMNAMAPT
SCHEMBL1663576 0.96 TP53 (0.45) TP53KDM4EGMNNLMNAMAPT
SCHEMBL9558017 0.94 GPR84 (0.41)
SCHEMBL3155145 0.92 TP53 (0.50) TP53KDM4EGMNNLMNAMAPT
SCHEMBL17099449 0.90 GPR84 (0.43) LMNA
SCHEMBL3490657 0.90 GPR84 (0.43) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1055697-C Phospholipi derivatives containing higher elements of the Vth main group ASTA MEDICA AG (DE) 2000-08-23 CN disclosed
US-5958906-A Phospholipid derivatives containing higher elements of the fifth main group ASTA-MEDICA AKTIENGESELLSCHAFT (DE) 1999-09-28 US disclosed
US-5637577-A TREATMENT OF POTOZOAL DISEASES ASTA MEDICA AKTIENGESELLSCHAFT (DE) 1997-06-10 US disclosed
US-5449798-A Phospholipid derivatives containing higher elements of the fifth group ASTA MEDICA AKTIENGESELLSCHAFT (DE) 1995-09-12 US disclosed
CN-1088583-A The phospholipid derivative that contains the 5th main group higher elements ASTA MEDICA AG (DE) 1994-06-29 CN disclosed
EP-0594999-A1 Phospholipid derivatives containing higher elements of the fifth main group ASTA Medica Aktiengesellschaft (DE) 1994-05-04 EP disclosed