Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.35 |
| ▸ | PDE4A | P27815 | 5/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.35 |
| ▸ | PDE2A | O00408 | 4/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413879 | 1.00 | KDM1A (0.36) | KDM1APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8378012 | 1.00 | KDM1A (0.36) | KDM1APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL9060720 | 0.90 | CYP2C9 (0.40) | KDM1APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL9225434 | 0.90 | CYP2C9 (0.40) | KDM1APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL9225443 | 0.90 | CYP2C9 (0.40) | KDM1APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8411600 | 0.88 | KDM1A (0.34) | KDM1APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8411606 | 0.88 | KDM1A (0.34) | KDM1APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8379549 | 0.88 | KDM1A (0.34) | KDM1APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8411574 | 0.87 | PDE4D (0.33) | KDM1APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8411577 | 0.87 | PDE4D (0.33) | KDM1APDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452460-B2 | ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM | MERCK PATENT GMBH (DE) | 1999-08-11 | — | — | EP | disclosed |
| US-5456860-A | Containing liquid crystal mixture based on dielectrically positive compounds which contain polar end group with specified lipophilicity parameter | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-10-10 | — | — | US | disclosed |
| US-5344587-A | Nitriles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-06 | — | — | US | disclosed |
| EP-0450354-A2 | Matrix-liquid crystal display | MERCK PATENT GmbH (DE) | 1991-10-09 | — | — | EP | disclosed |
| WO-1991005029-A1 | ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-18 | — | — | WO | disclosed |