Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 5/20 | 0.42 |
| ▸ | ACHE | P22303 | 5/20 | 0.42 |
| ▸ | GSR | P00390 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4199059 | 0.90 | EGFR (0.54) | EGFRBCHEACHEGSRKMT2A | |
| SCHEMBL4199068 | 0.90 | EGFR (0.54) | EGFRBCHEACHEGSRKMT2A | |
| SCHEMBL3953943 | 0.88 | EGFR (0.49) | EGFRBCHEACHEGSRKMT2A | |
| SCHEMBL842362 | 0.87 | GSR (0.42) | BCHEACHEGSRKMT2ACHRM1 | |
| SCHEMBL3167025 | 0.83 | EGFR (0.57) | EGFRKMT2A | |
| SCHEMBL6096675 | 0.80 | BRD4 (0.41) | KMT2ABRD4 | |
| SCHEMBL8125697 | 0.80 | BCHE (0.47) | BCHEACHEKMT2ABRD4 | |
| SCHEMBL6094679 | 0.79 | BRD4 (0.40) | KMT2ABRD4 | |
| SCHEMBL563646 | 0.79 | KDM4E (0.39) | KMT2ABRD4 | |
| SCHEMBL8137366 | 0.78 | BCHE (0.47) | BCHEACHEKMT2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143270-B2 | 2-amino 1H-in-imidazo ring systems and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-03-27 | — | — | US | disclosed |