SCHEMBL8137366

SCHEMBL8137366

CC(C)(C)OC(=O)NCCCCNc1c([N+](=O)[O-])c(Cl)nc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BCHE P06276 5/20 0.47
ACHE P22303 5/20 0.47
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
GAA P10253 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
BRD4 O60885 3/20 0.45
ACACB O00763 1/20 0.44
ACACA Q13085 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8125697 0.98 BCHE (0.47) BCHEACHEMEN1NPC1GAA
SCHEMBL843596 0.94 BCHE (0.49) BCHEACHEMEN1NPC1GAA
SCHEMBL31037654 0.90 MEN1 (0.46) BCHEACHEMEN1NPC1GAA
SCHEMBL212541 0.87 EGFR (0.55) BCHEMEN1NPC1GAARAB9A
SCHEMBL29381474 0.87 EGFR (0.55) BCHEMEN1NPC1GAARAB9A
SCHEMBL31337604 0.87 BRD4 (0.44) BCHEACHEBRD4
SCHEMBL22445116 0.87 BRD4 (0.46) BRD4
SCHEMBL17675518 0.86 BCHE (0.48) BCHEACHEMEN1KMT2A
SCHEMBL17675516 0.86 BCHE (0.48) BCHEACHEMEN1KMT2A
SCHEMBL212372 0.85 EGFR (0.48) MEN1NPC1GAARAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11547761-B1 Antibody adjuvant conjugates THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-01-10 US disclosed
US-11110178-B2 Antibody adjuvant conjugates THE BOARD OF TRUSTEES OF THE LELAND STANDFORD JUNIOR UNIVERSITY (US) 2021-09-07 US disclosed
US-20200206357-A1 ANTIBODY ADJUVANT CONJUGATES BOLT BIOTHERAPEUTICS, INC. 2020-07-02 US disclosed
US-10675358-B2 Antibody adjuvant conjugates THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2020-06-09 US disclosed
US-20190076547-A1 ANTIBODY ADJUVANT CONJUGATES BOLT BIOTHERAPEUTICS, INC. 2019-03-14 US disclosed
US-6069149-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS TERUMO KABUSHIKI KAISHA (JP) 2000-05-30 US disclosed
EP-0894797-A1 NOVEL AMIDE DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF TERUMO KABUSHIKI KAISHA (JP) 1999-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200206357-A1 ANTIBODY ADJUVANT CONJUGATES FCGR1A, FCGR3B, FCGR2A BCHE 474/4885ACHE 1269/4885MEN1 3653/4885
US-10675358-B2 Antibody adjuvant conjugates FCGR1A, FCGR3B, FCGR2A BCHE 474/4885ACHE 1269/4885MEN1 3653/4885
US-20190076547-A1 ANTIBODY ADJUVANT CONJUGATES FCGR1A, FCGR3B, FCGR2A BCHE 546/4885ACHE 1268/4885MEN1 3734/4885
US-11547761-B1 Antibody adjuvant conjugates FCGR1A, FCGR3B, FCGR2A BCHE 474/4885ACHE 1269/4885MEN1 3653/4885
US-11110178-B2 Antibody adjuvant conjugates FCGR1A, FCGR3B, FCGR2A BCHE 474/4885ACHE 1269/4885MEN1 3653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.