Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5682911 | 0.95 | CASP1 (0.68) | CASP1 | |
| SCHEMBL8410279 | 0.84 | CASP1 (0.68) | CASP1 | |
| SCHEMBL8034238 | 0.84 | CASP1 (0.68) | CASP1 | |
| SCHEMBL5678978 | 0.83 | CASP1 (0.70) | CASP1 | |
| SCHEMBL5682795 | 0.81 | CASP1 (0.77) | CASP1 | |
| SCHEMBL8410660 | 0.81 | CASP1 (0.58) | CASP1 | |
| SCHEMBL5678977 | 0.80 | CASP1 (0.71) | CASP1 | |
| SCHEMBL5681298 | 0.79 | CASP1 (0.76) | CASP1 | |
| SCHEMBL5683297 | 0.78 | CASP1 (0.78) | CASP1 | |
| SCHEMBL5682775 | 0.78 | CASP1 (0.74) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0932600-A2 | SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1$g(b) CONVERTING ENZYME INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998016504-A2 | SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1β CONVERTING ENZYME INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |