Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155513 | 0.81 | PTGIR (0.69) | PTGIRTBXAS1KDM4CPTGDR2SIGMAR1 | |
| SCHEMBL9155480 | 0.81 | PTGIR (0.68) | PTGIRTBXAS1KDM4CPTGDR2SIGMAR1 | |
| SCHEMBL8410712 | 0.80 | PTGIR (0.57) | PTGIRTBXAS1KDM4CPTGDR2SIGMAR1 | |
| SCHEMBL8858587 | 0.80 | PTGIR (0.72) | PTGIRTBXAS1PTGDR2SIGMAR1HTR1A | |
| SCHEMBL9050868 | 0.78 | PTGIR (0.64) | PTGIRTBXAS1KDM4CPTGDR2 | |
| SCHEMBL8809328 | 0.78 | PTGIR (0.58) | PTGIRTBXAS1 | |
| SCHEMBL8574945 | 0.78 | PTGIR (0.61) | PTGIRTBXAS1KDM4CPTGDR2 | |
| SCHEMBL9017264 | 0.77 | PTGIR (0.63) | PTGIRTBXAS1KDM4CPTGDR2 | |
| SCHEMBL9151307 | 0.77 | PTGIR (0.63) | PTGIRTBXAS1KDM4CPTGDR2SIGMAR1 | |
| SCHEMBL8410932 | 0.76 | PTGIR (0.61) | PTGIRTBXAS1KDM4CPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |