Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.63 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050868 | 0.88 | PTGIR (0.64) | PTGIRTBXAS1PTGDR2KDM4CKDM4E | |
| SCHEMBL9155513 | 0.87 | PTGIR (0.69) | PTGIRTBXAS1PTGDR2KDM4C | |
| SCHEMBL9155480 | 0.86 | PTGIR (0.68) | PTGIRTBXAS1PTGDR2KDM4C | |
| SCHEMBL8858587 | 0.85 | PTGIR (0.72) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9151307 | 0.82 | PTGIR (0.63) | PTGIRTBXAS1PTGDR2KDM4C | |
| SCHEMBL1838407 | 0.82 | PTGIR (0.56) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL1838402 | 0.82 | PTGIR (0.56) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL8858726 | 0.82 | PTGIR (0.56) | PTGIRTBXAS1PTGDR2KDM4EALDH1A1 | |
| SCHEMBL8858484 | 0.81 | PTGIR (0.61) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9050622 | 0.80 | PTGIR (0.62) | PTGIRTBXAS1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |