Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 0.40 |
| ▸ | RXRA | P19793 | 9/20 | 0.38 |
| ▸ | RXRB | P28702 | 9/20 | 0.38 |
| ▸ | RXRG | P48443 | 6/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413670 | 0.83 | PTGIR (0.38) | PTGIRRXRARXRBRXRGMRGPRX4 | |
| SCHEMBL8411056 | 0.83 | PTGIR (0.42) | PTGIRRXRARXRBRXRGPRMT5 | |
| SCHEMBL8410745 | 0.83 | PTGIR (0.51) | PTGIRRXRARXRBRXRGPRMT5 | |
| SCHEMBL8414114 | 0.82 | PTGIR (0.38) | PTGIRRXRARXRBRXRGPRMT5 | |
| SCHEMBL8414258 | 0.80 | RXRA (0.40) | PTGIRRXRARXRBRXRGPRMT5 | |
| SCHEMBL8414257 | 0.80 | PTGIR (0.38) | PTGIRRXRARXRBRXRGPRMT5 | |
| SCHEMBL8414222 | 0.78 | PTGIR (0.45) | PTGIRRXRARXRBRXRGPRMT5 | |
| SCHEMBL8519037 | 0.78 | PTGIR (0.46) | PTGIRRXRARXRBRXRGPRMT5 | |
| SCHEMBL8413364 | 0.78 | PTGIR (0.46) | PTGIRRXRARXRBRXRGPRMT5 | |
| SCHEMBL8410887 | 0.78 | PTGIR (0.50) | PTGIRRXRARXRBRXRGPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | claimed |
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |