Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414452 | 0.80 | PTGIR (0.60) | PTGIRTBXAS1PTGDR2ALDH1A1PTGDR | |
| SCHEMBL8410702 | 0.75 | PTGIR (0.60) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL8413331 | 0.72 | PTGIR (0.39) | PTGIRPTGDR2PTGDR | |
| SCHEMBL8809708 | 0.72 | PTGIR (0.39) | PTGIRPTGDR2PTGDR | |
| SCHEMBL8411290 | 0.72 | PTGIR (0.56) | PTGIRPTGDR2KDM4EALDH1A1HPGD | |
| SCHEMBL8411284 | 0.72 | PTGIR (0.50) | PTGIRPTGDR2KDM4EALDH1A1HPGD | |
| SCHEMBL8411445 | 0.70 | PTGIR (0.58) | PTGIRPTGDR2 | |
| SCHEMBL8811745 | 0.70 | PTGIR (0.44) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL8809752 | 0.70 | PTGIR (0.44) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL8414276 | 0.69 | PTGIR (0.49) | PTGIRPTGDR2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |