Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413331 | 1.00 | PTGIR (0.39) | PTGIRMEN1KMT2ASMN1; SMN2MRGPRX4 | |
| SCHEMBL8811752 | 0.88 | SIGMAR1 (0.37) | MEN1KMT2ASMN1; SMN2MRGPRX4SIGMAR1 | |
| SCHEMBL8811745 | 0.77 | PTGIR (0.44) | PTGIRPTGDR2 | |
| SCHEMBL8809752 | 0.77 | PTGIR (0.44) | PTGIRPTGDR2 | |
| SCHEMBL8414452 | 0.77 | PTGIR (0.60) | PTGIRMEN1KMT2ASMN1; SMN2MRGPRX4 | |
| SCHEMBL8414316 | 0.76 | ABCB1 (0.43) | PTGIRMEN1KMT2ASMN1; SMN2MRGPRX4 | |
| SCHEMBL8414317 | 0.76 | ABCB1 (0.43) | PTGIRMEN1KMT2ASMN1; SMN2MRGPRX4 | |
| SCHEMBL8410702 | 0.74 | PTGIR (0.60) | PTGIRSIGMAR1HTR1APTGDR2 | |
| SCHEMBL8411299 | 0.74 | PTGIR (0.41) | PTGIRSMN1; SMN2PPARDPTGDR | |
| SCHEMBL8809056 | 0.74 | PTGIR (0.39) | PTGIRMEN1KMT2ASMN1; SMN2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| US-5389666-A | Administering for treatment and prevention of thrombosis, arteriosclerosis, ischemic heart diseases, gastric ulcer or hypertension | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |