Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10346259 | 0.94 | MAPK1 (0.71) | MAPK1HDAC8HDAC4HDAC2KIF11 | |
| SCHEMBL44643 | 0.86 | MAPK1 (0.58) | MAPK1HDAC8HDAC4HDAC2KIF11 | |
| SCHEMBL2865735 | 0.86 | MAPK1 (0.81) | MAPK1ESR1ESR2CYP3A4ALDH1A1 | |
| SCHEMBL129151 | 0.84 | HDAC8 (0.56) | HDAC8HDAC4HDAC2KIF11ACHE | |
| SCHEMBL31578994 | 0.84 | MAPK1 (0.56) | MAPK1HDAC8HDAC4HDAC2KIF11 | |
| SCHEMBL12500725 | 0.84 | HDAC8 (0.44) | MAPK1HDAC8HDAC4HDAC2KIF11 | |
| Methoxymethane SCHEMBL28022475 | 0.82 | HDAC8 (0.50) | MAPK1HDAC8HDAC4HDAC2KIF11 | |
| Hydrogen Peroxide SCHEMBL20240069 | 0.82 | MAPK1 (0.60) | MAPK1HDAC8HDAC4HDAC2RXRA | |
| SCHEMBL19327212 | 0.82 | MAPK1 (0.60) | MAPK1HDAC8HDAC4HDAC2ESR1 | |
| Water SCHEMBL29289408 | 0.82 | HDAC8 (0.54) | HDAC8HDAC4HDAC2KIF11ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613154-B1 | Process for preparing a polyethylene composition for use in insulations and joints of extra-high voltage power cables | FUJIKURA LTD (JP) | 1999-08-18 | — | — | EP | disclosed |
| EP-0613154-A2 | Polyethylene composition for use in insulations and joints of extra-high voltage power cables, and an extra-high voltage power cable and joint therefor employing this polyethylene composition | FUJIKURA LTD. (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-4134927-A | EXTRUDING ETHYLENE COPOLYMER, UNSATURATED DICARBOXYLIC ACID, AND AN ALKYL PEROXIDE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1979-01-16 | — | — | US | disclosed |