Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27302332 | 0.85 | MEN1 (0.64) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL27588745 | 0.83 | MEN1 (0.62) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL2866680 | 0.82 | MEN1 (0.60) | MEN1KMT2AUSP2GAAKEAP1 | |
| 2,4-Dihydroxybenzophenone SCHEMBL28311098 | 0.81 | MEN1 (0.86) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL27651620 | 0.81 | MEN1 (0.58) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL367932 | 0.80 | L3MBTL1 (0.55) | GAAALDH1A1CYP1A2CYP2C19MAPK1 | |
| SCHEMBL28933964 | 0.80 | MEN1 (0.57) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL8415153 | 0.79 | LIG1 (0.59) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL2862128 | 0.78 | MEN1 (0.55) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL30523219 | 0.78 | MEN1 (0.55) | MEN1KMT2AUSP2GAAKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5986136-A | Photolabeling reagent | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1999-11-16 | — | — | US | disclosed |