Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31236067 | 1.00 | TAS2R14 (0.61) | TAS2R14KDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6766335 | 0.88 | GAA (0.54) | TAS2R14ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17531760 | 0.82 | MAPT (0.49) | TAS2R14KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL2194658 | 0.80 | TAS2R14 (0.61) | TAS2R14KDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL11351333 | 0.80 | TAS2R14 (0.61) | TAS2R14KDM4EGRIN2DGRIN3BGRIN1 | |
| Potassium Ion SCHEMBL11361356 | 0.80 | TAS2R14 (0.61) | TAS2R14KDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL11358861 | 0.80 | TAS2R14 (0.61) | TAS2R14KDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL11358865 | 0.80 | TAS2R14 (0.61) | TAS2R14KDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL11361353 | 0.78 | TAS2R14 (0.59) | TAS2R14KDM4EGRIN2DGRIN3BGRIN1 | |
| Potassium SCHEMBL11361366 | 0.78 | TAS2R14 (0.59) | TAS2R14KDM4EGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912245-A | AMPA AND KAINATE ANTAGONISTS. | EGIS GYOGYSZERGYAR RT. (HU) | 1999-06-15 | — | — | US | disclosed |
| EP-0759910-A1 | ACID AMIDE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | EGIS GYOGYSZERGYAR RT. (HU) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031443-A1 | ACID AMIDE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | EGIS Gyógyszergyár Rt. (HU) | 1995-11-23 | — | — | WO | disclosed |