Methoxymethane

Methoxymethane

SCHEMBL8415315

COC.O=C(O)c1ccc(C(=O)O)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.65
ALDH1A1 P00352 7/20 0.65
LMNA P02545 3/20 0.65
L3MBTL1 Q9Y468 2/20 0.65
KMT2A Q03164 6/20 0.57
MEN1 O00255 5/20 0.57
MAPK1 P28482 4/20 0.57
POLB P06746 3/20 0.57
THRB P10828 2/20 0.57
RECQL P46063 1/20 0.57
KDM4E B2RXH2 4/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
MMP14 P50281 1/20 0.57
TTR P02766 2/20 0.56
MITF O75030 1/20 0.53
PKM P14618 2/20 0.53
USP2 O75604 2/20 0.51
MCL1 Q07820 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
CYP1A2 P05177 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29568790 0.92 MAPT (0.74) MAPTALDH1A1LMNAL3MBTL1KMT2A
SCHEMBL71118 0.92 MAPT (0.74) MAPTALDH1A1LMNAL3MBTL1KMT2A
SCHEMBL16224285 0.88 MAPT (0.69) MAPTALDH1A1LMNAL3MBTL1KMT2A
SCHEMBL11878475 0.81 MAPT (0.61) MAPTALDH1A1LMNAL3MBTL1KMT2A
SCHEMBL7533991 0.81 ADORA2A (0.68) MAPTALDH1A1LMNAL3MBTL1KMT2A
SCHEMBL17718222 0.81 MAPT (0.51) MAPTALDH1A1LMNAL3MBTL1KMT2A
SCHEMBL581124 0.78 ALDH1A1 (1.00) MAPTALDH1A1LMNAL3MBTL1KMT2A
Anthraquinone SCHEMBL8941397 0.78 ALDH1A1 (1.00) MAPTALDH1A1LMNAL3MBTL1KMT2A
SCHEMBL461660 0.78 ALDH1A1 (1.00) MAPTALDH1A1LMNAL3MBTL1KMT2A
SCHEMBL28247060 0.78 MAPT (0.56) MAPTALDH1A1LMNAL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934247-A1 PHOTOINITIATORS Lambson Fine Chemicals Limited (GB) 1999-08-11 EP disclosed
WO-1997049664-A1 PHOTOINITIATORS LAMBSON FINE CHEMICALS LIMITED (GB) 1997-12-31 WO disclosed