Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412870 | 0.80 | CA4 (0.42) | CA4ESR1ESR2CA12CA1 | |
| SCHEMBL8412803 | 0.80 | CA4 (0.42) | CA4ESR1ESR2CA12CA1 | |
| SCHEMBL8415029 | 0.80 | ESR1 (0.38) | CA4ESR1ESR2CA12CA1 | |
| SCHEMBL8638843 | 0.80 | ESR1 (0.38) | CA4ESR1ESR2CA12CA1 | |
| SCHEMBL8416097 | 0.80 | ESR1 (0.38) | CA4ESR1ESR2CA12CA1 | |
| SCHEMBL8412824 | 0.80 | CA4 (0.42) | CA4ESR1ESR2CA12CA1 | |
| SCHEMBL48955 | 0.79 | ESR1 (0.41) | CA4ESR1ESR2CA12CA1 | |
| SCHEMBL8415126 | 0.78 | CA4 (0.40) | CA4ESR1ESR2CA12CA1 | |
| SCHEMBL8414396 | 0.78 | CA4 (0.40) | CA4ESR1ESR2CA12CA1 | |
| SCHEMBL8642194 | 0.78 | ESR1 (0.37) | CA4ESR1ESR2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669363-B1 | Process for preparing polyorganosilane | TOSHIBA SILICONE (JP) | 1999-08-18 | — | — | EP | disclosed |
| EP-0641820-B1 | Organosilicon polymer and process for the preparation thereof | TOSHIBA SILICONE (JP) | 1998-08-12 | — | — | EP | disclosed |
| US-5633312-A | Process for preparing polyorganosilane | TOSHIBA SILICONE CO., LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5489662-A | Process for the preparation of organosilicon polymer | TOSHIBA SILICONE CO., LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0669363-A2 | Process for preparing polyorganosilane | TOSHIBA SILICONE CO., LTD. (JP) | 1995-08-30 | — | — | EP | disclosed |
| EP-0641820-A1 | Process for the preparation of organosilicon polymer | TOSHIBA SILICONE CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |