SCHEMBL48955

SCHEMBL48955

CO[Si](C)(C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
CA4 P22748 2/20 0.39
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
POLB P06746 2/20 0.34
ALDH1A1 P00352 3/20 0.33
NR1H2 P55055 2/20 0.33
NR1H3 Q13133 2/20 0.33
LTA4H P09960 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
MAPT P10636 2/20 0.32
TSHR P16473 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12977080 0.91 ESR1 (0.40) ESR1ESR2CA4POLBNR1H2
SCHEMBL6287529 0.91 ESR1 (0.35) ESR1ESR2CA4CA12CA1
SCHEMBL16487200 0.85 NPC1 (0.41) POLBALDH1A1NPC1RAB9ACYP1A2
SCHEMBL676007 0.85 CA12 (0.30) CA12CA1CA2CA7CA9
SCHEMBL2959740 0.81 ACHE (0.34) ESR1ESR2CA1CA2CA7
SCHEMBL11946980 0.80 ESR1 (0.35) ESR1ESR2CA4POLB
SCHEMBL18094256 0.80 ESR1 (0.35) ESR1ESR2CA4POLB
SCHEMBL15471184 0.80 APP (0.48) CA12CA1CA2CA9ALDH1A1
SCHEMBL5091208 0.80 ESR1 (0.32) ESR1ESR2CA4ALDH1A1NPC1
SCHEMBL6749673 0.80 ALDH1A1 (0.43) ESR1ESR2ALDH1A1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1624 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634324-A1 AMPHIPHILIC ABRASIVE PARTICLES AND THEIR USE FOR CHEMICAL MECHANICAL PLANARIZATION Versum Materials US, LLC (US) 2025-10-22 EP claimed
CN-120005195-A Composition for room temperature vulcanized transparent silicone rubber and preparation method thereof 湖北鑫金鹏新材料有限公司 2025-05-16 CN claimed
CN-119552510-A High-refractive-index low-haze addition type liquid silicone rubber and preparation method thereof 湖北兴瑞硅材料有限公司 2025-03-04 CN claimed
CN-119481269-A Li/CFxElectrolyte for battery and Li/CF containing the samexBattery cell 惠州亿纬锂能股份有限公司 2025-02-18 CN claimed
CN-119431794-A Organosilicon tackifier and preparation method and application thereof 杭州之江有机硅化工有限公司 2025-02-14 CN claimed
CN-117866204-B Silicon-containing surface modifier and etching-resistant agent underlayer film composition, and preparation method and application thereof 福建泓光半导体材料有限公司 2024-12-13 CN claimed
CN-119100393-A Method for preparing high-purity nano silicon-carbon-oxygen ceramic powder by microwave induction graphite tube-array fluidized bed pyrolysis of silicon-carbon composite aerogel 绍兴晶彩科技有限公司 2024-12-10 CN claimed
CN-119100394-A Method for preparing high-purity nano silicon carbide powder by combining microwave heating technology with self-suspension carbothermal reduction technology 绍兴晶彩科技有限公司 2024-12-10 CN claimed
US-20240309144-A1 SILANE MODIFIED ALIPHATIC POLYUREA EVONIK OPERATIONS GMBH (DE) 2024-09-19 US claimed
WO-2024129435-A1 AMPHIPHILIC ABRASIVE PARTICLES AND THEIR USE FOR CHEMICAL MECHANICAL PLANARIZATION VERSUM MATERIALS US, LLC (US) 2024-06-20 WO claimed
US-20060251848-A1 Optical information storage medium possessing a multilayer coating MOMENTIVE PERFORMANCE MATERIALS INC. 2006-11-09 US claimed
WO-2005124792-A1 ANTI-CORROSION ADDITIVE FOR ELECTRICAL CABLE RESTORATION FLUIDS DOW CORNING CORPORATION (US) 2005-12-29 WO claimed
US-6697712-B1 Distributed cable feed system and method UTILX CORPORATION 2004-02-24 US claimed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP claimed
EP-0457175-B1 Method of purification of alkoxysilanes TOSHIBA SILICONE (JP) 1997-02-12 EP claimed
EP-0278157-B1 A RUBBER COMPOSITION Shin-Etsu Chemical Co., Ltd. (JP) 1993-06-16 EP claimed
US-5104999-A METHOD OF PURIFICATION OF ALKOXYSILANES TOSHIBA SILICONE CO., LTD. (JP) 1992-04-14 US claimed
EP-0457175-A2 Method of purification of alkoxysilanes TOSHIBA SILICONE CO., LTD. (JP) 1991-11-21 EP claimed
EP-0278157-A2 A rubber composition Shin-Etsu Chemical Co., Ltd. (JP) 1988-08-17 EP claimed
US-4714733-A VULCANIZABLE BLEND OF RUBBER, UNSATURATED POLYSILOXANE, SILICA FILLER, AND THIOCARBAMYL-CONTAINING ORGANOSILANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1987-12-22 US claimed