SCHEMBL8415484

SCHEMBL8415484

CCO[Si](OCC)(OCC)c1ccccc1.[SrH2]

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.35
TP53 P04637 2/20 0.35
ALDH1A1 P00352 3/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
GRM5 P41594 1/20 0.33
MAPK1 P28482 1/20 0.33
RELA Q04206 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
TSHR P16473 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
KCNH2 Q12809 1/20 0.31
GLA P06280 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29900 0.98 LTA4H (0.37) LTA4HTP53ALDH1A1NPC1RAB9A
SCHEMBL10495731 0.95 LTA4H (0.35) LTA4HTP53ALDH1A1NPC1RAB9A
Ammonia Solution, Strong SCHEMBL28965973 0.95 LTA4H (0.35) LTA4HTP53ALDH1A1NPC1RAB9A
Ethane SCHEMBL28129535 0.95 LTA4H (0.35) LTA4HTP53ALDH1A1NPC1RAB9A
Methane SCHEMBL27804293 0.95 LTA4H (0.35) LTA4HTP53ALDH1A1NPC1RAB9A
Water SCHEMBL27611436 0.95 LTA4H (0.35) LTA4HTP53ALDH1A1NPC1RAB9A
Chloromethane SCHEMBL27769943 0.93 LTA4H (0.34) LTA4HTP53ALDH1A1NPC1RAB9A
Fluoride SCHEMBL27639639 0.93 LTA4H (0.34) LTA4HTP53ALDH1A1NPC1RAB9A
Methyl Alcohol SCHEMBL27925740 0.93 ESR1 (0.35) LTA4HTP53ALDH1A1NPC1RAB9A
SCHEMBL29156180 0.91 KCNH2 (0.33) LTA4HTP53ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5908879-A A POLYSILOXANE COATING ON THE SURFACE OF THE PARTICLE. KURARAY CO., LTD. (JP) 1999-06-01 US disclosed