Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416429 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TDP1SMN1; SMN2GBA1EPHX2 | |
| SCHEMBL11170139 | 0.80 | GBA1 (0.37) | ALDH1A1TDP1GBA1EPHX2 | |
| SCHEMBL11177301 | 0.80 | GBA1 (0.37) | ALDH1A1TDP1GBA1EPHX2 | |
| SCHEMBL11170469 | 0.80 | GBA1 (0.37) | ALDH1A1TDP1GBA1EPHX2 | |
| SCHEMBL11172698 | 0.80 | GBA1 (0.37) | ALDH1A1TDP1GBA1EPHX2 | |
| SCHEMBL11009382 | 0.79 | TSHR (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL11166731 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TDP1SMN1; SMN2GBA1EPHX1 | |
| SCHEMBL11174237 | 0.77 | GBA1 (0.39) | ALDH1A1TDP1GBA1EPHX2 | |
| SCHEMBL4347877 | 0.77 | GBA1 (0.39) | ALDH1A1TDP1GBA1EPHX2 | |
| SCHEMBL22371937 | 0.77 | GBA1 (0.39) | ALDH1A1TDP1GBA1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634450-B1 | Polyether with releasably bound sterically hindered amines as stabilizing agents | CIBA GEIGY AG (CH) | 1999-09-08 | — | — | EP | disclosed |
| US-5534618-A | Polyethers containing hindered amines which can be cleaved off as stabilizers | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0634450-A2 | Polyether with releasably bound sterically hindered amines as stabilizing agents | CIBA-GEIGY AG (CH) | 1995-01-18 | — | — | EP | disclosed |