Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146216 | 1.00 | NOD1 (0.56) | NOD1CA2MAPK1ALOX15GGT1 | |
| SCHEMBL9831562 | 0.94 | NOD1 (0.58) | NOD1CA2MAPK1ITGB3ITGA2B | |
| SCHEMBL3416074 | 0.94 | NOD1 (0.58) | NOD1CA2MAPK1ITGB3ITGA2B | |
| SCHEMBL30957009 | 0.92 | NOD1 (0.61) | NOD1ITGB3ITGA2BGPR84FFAR1 | |
| SCHEMBL28794255 | 0.92 | NOD1 (0.61) | NOD1ITGB3ITGA2BGPR84FFAR1 | |
| SCHEMBL6760747 | 0.92 | NOD1 (0.49) | NOD1CA2MAPK1GGT1ACHE | |
| SCHEMBL28061203 | 0.90 | NOD1 (0.58) | NOD1ITGB3ITGA2BGPR84FFAR1 | |
| SCHEMBL4443564 | 0.89 | NOD1 (0.51) | NOD1ALOX15GPR84FFAR1FOLH1 | |
| SCHEMBL15955860 | 0.88 | NOD1 (0.50) | NOD1CA2MAPK1ALOX15GGT1 | |
| SCHEMBL15955861 | 0.88 | NOD1 (0.50) | NOD1CA2MAPK1ALOX15GGT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3938377-A1 | CYCLIC PEPTIDE ANTIBIOTICS | F. Hoffmann-La Roche AG (CH) | 2022-01-19 | — | — | EP | disclosed |
| WO-2020185999-A1 | CYCLIC PEPTIDE ANTIBIOTICS | GENENTECH, INC. (US) | 2020-09-17 | — | — | WO | disclosed |
| EP-0934260-A1 | N ALPHA-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | Hyundai Pharm. Ind. Co., Ltd. (KR) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017638-A1 | Nα-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | HYUNDAI PHARM. IND. CO., LTD. (KR) | 1998-04-30 | — | — | WO | disclosed |