Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | BACE1 | P56817 | 8/20 | 0.57 |
| ▸ | ACHE | P22303 | 7/20 | 0.57 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415734 | 1.00 | KMT2A (0.63) | KMT2ABACE1ACHEBCHEMEN1 | |
| SCHEMBL8418576 | 0.98 | KMT2A (0.67) | KMT2ABACE1ACHEBCHEMEN1 | |
| SCHEMBL8418574 | 0.98 | KMT2A (0.67) | KMT2ABACE1ACHEBCHEMEN1 | |
| SCHEMBL28259545 | 0.98 | KMT2A (0.67) | KMT2ABACE1ACHEBCHEMEN1 | |
| SCHEMBL8416726 | 0.96 | KMT2A (0.58) | KMT2ABACE1ACHEBCHEMEN1 | |
| SCHEMBL8416725 | 0.96 | KMT2A (0.58) | KMT2ABACE1ACHEBCHEMEN1 | |
| Methylamine SCHEMBL28653048 | 0.92 | KMT2A (0.61) | KMT2ABACE1ACHEBCHEMEN1 | |
| SCHEMBL15172985 | 0.91 | BACE1 (0.61) | KMT2ABACE1ACHEBCHEALDH1A1 | |
| SCHEMBL2726398 | 0.91 | BACE1 (0.61) | KMT2ABACE1ACHEBCHEALDH1A1 | |
| SCHEMBL15172984 | 0.91 | BACE1 (0.61) | KMT2ABACE1ACHEBCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714885-B1 | Preparation process of aminoacetamide derivative | EISAI CO LTD (JP) | 1999-09-01 | — | — | EP | disclosed |
| EP-0714885-A2 | Preparation process of aminoacetamide derivative | EISAI CHEMICAL CO., LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |