SCHEMBL8418576

SCHEMBL8418576

C(=NC1CCCCC1)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.67
BACE1 P56817 8/20 0.56
ACHE P22303 7/20 0.56
ALDH1A1 P00352 4/20 0.49
MAPT P10636 3/20 0.49
BCHE P06276 3/20 0.49
MPI P34949 1/20 0.49
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MEN1 O00255 1/20 0.45
THRB P10828 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8418574 1.00 KMT2A (0.67) KMT2ABACE1ACHEALDH1A1MAPT
SCHEMBL28259545 1.00 KMT2A (0.67) KMT2ABACE1ACHEALDH1A1MAPT
SCHEMBL8415735 0.98 KMT2A (0.63) KMT2ABACE1ACHEALDH1A1MAPT
SCHEMBL8415734 0.98 KMT2A (0.63) KMT2ABACE1ACHEALDH1A1MAPT
Methylamine SCHEMBL28653048 0.94 KMT2A (0.61) KMT2ABACE1ACHEALDH1A1MAPT
SCHEMBL8416726 0.94 KMT2A (0.58) KMT2ABACE1ACHEALDH1A1MAPT
SCHEMBL8416725 0.94 KMT2A (0.58) KMT2ABACE1ACHEALDH1A1MAPT
SCHEMBL10672579 0.89 KMT2A (0.56) KMT2ABACE1ACHEALDH1A1MAPT
SCHEMBL10672591 0.89 KMT2A (0.56) KMT2ABACE1ACHEALDH1A1MAPT
SCHEMBL2726396 0.89 BACE1 (0.61) KMT2ABACE1ACHEALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5247009-A Reacted with an imine and an acid halide, tires NIPPON ZEON CO., LTD. (JP) 1993-09-21 US claimed
US-4677153-A REACTING WITH AN ACYL HALIDE AND NIPPON ZEON CO., LTD. (JP) 1987-06-30 US claimed
US-20260137083-A1 HETEROCYCLYL PYRIDAZINE AS FUNGICIDAL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 2026-05-21 US disclosed
US-12565489-B2 Heterocyclyl pyrimidines and triazines as novel fungicides BAYER AKTIENGESELLSCHAFT (DE) 2026-03-03 US disclosed
US-12552748-B2 Pyridine (thio)amides as fungicidal compounds BAYER AKTIENGESELLSCHAFT (DE) 2026-02-17 US disclosed
US-12543738-B2 3-(pyridazin-4-yl)-5,6-dihydro-4H-1,2,4-oxadiazine derivatives as fungicides for crop protection BAYER AKTIENGESELLSCHAFT (DE) 2026-02-10 US disclosed
EP-4149929-B1 TRIAZINE AND PYRIMIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS BAYER AG (DE) 2026-01-28 EP disclosed
US-12534456-B2 Heterocyclyl pyridines as novel fungicides BAYER AKTIENGESELLSCHAFT (DE) 2026-01-27 US disclosed
US-12520844-B2 Triazine and pyrimidine (thio)amides as fungicidal compounds BAYER AKTIENGESELLSCHAFT (DE) 2026-01-13 US disclosed
US-12501900-B2 Heterocyclyl pyridazine as fungicidal compounds BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 US disclosed
US-12414565-B2 Pyridazine (THIO)amides as fungicidal compounds BAYER AKTIENGESELLSCHAFT (DE) 2025-09-16 US disclosed
EP-0388921-A2 Additive for organic solvent or thermoplastic polymer NIPPON ZEON CO., LTD. (JP) 1990-09-26 EP disclosed
EP-0198294-B1 METHOD FOR MODIFYING RUBBERS NIPPON ZEON CO., LTD. (JP) 1989-01-04 EP disclosed
EP-0244603-A2 Polymers containing amino groups, their manufacture and their use BASF Aktiengesellschaft (DE) 1987-11-11 EP disclosed
US-4677153-A REACTING WITH AN ACYL HALIDE AND NIPPON ZEON CO., LTD. (JP) 1987-06-30 US disclosed
EP-0198294-A1 Method for modifying rubbers NIPPON ZEON CO., LTD. (JP) 1986-10-22 EP disclosed
US-4248677-A ELECTROCHEMICAL REDUCTION OF IMINES TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1981-02-03 US disclosed
US-4163024-A NICKEL CATALYST STUDIENGESELLSCHAFT KOHLE MBH. (DE) 1979-07-31 US disclosed
US-3970620-A Polyvinylchloride compositions for frothing DIAMOND SHAMROCK CORPORATION (US) 1976-07-20 US disclosed
US-3945955-A OPEN-CELLED FOAMS BY MECHANICAL WHIPPING DIAMOND SHAMROCK CORPORATION (US) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12414565-B2 Pyridazine (THIO)amides as fungicidal compounds PNPO, TPMT, BLVRB KMT2A 2136/4885BACE1 3480/4885ACHE 618/4885
US-12565489-B2 Heterocyclyl pyrimidines and triazines as novel fungicides CBR1, CBR3, NOX1 KMT2A 1606/4885BACE1 3679/4885ACHE 4185/4885
US-12543738-B2 3-(pyridazin-4-yl)-5,6-dihydro-4H-1,2,4-oxadiazine derivatives as fungicides for crop protection CYP4Z1, HPD, CYP4B1 KMT2A 472/4885BACE1 2612/4885ACHE 1127/4885
US-12501900-B2 Heterocyclyl pyridazine as fungicidal compounds PNPO, PDXK, BLVRB KMT2A 2293/4885BACE1 3073/4885ACHE 1185/4885
US-20260137083-A1 HETEROCYCLYL PYRIDAZINE AS FUNGICIDAL COMPOUNDS CBR1, CBR3, CYC1 KMT2A 2563/4885BACE1 3546/4885ACHE 3988/4885
US-12534456-B2 Heterocyclyl pyridines as novel fungicides CBR1, CBR3, NOX1 KMT2A 1948/4885BACE1 3468/4885ACHE 3966/4885
US-12552748-B2 Pyridine (thio)amides as fungicidal compounds CBR1, CBR3, TH KMT2A 3342/4885BACE1 4513/4885ACHE 3206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.