⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL456806 | 0.88 | — | — | |
| Morpholine SCHEMBL11338140 | 0.85 | MEN1 (0.65) | — | |
| Morpholine SCHEMBL7131082 | 0.82 | — | — | |
| Morpholine SCHEMBL2744013 | 0.82 | — | — | |
| Morpholine SCHEMBL1121824 | 0.82 | — | — | |
| Morpholine SCHEMBL1579459 | 0.82 | — | — | |
| Morpholine SCHEMBL28279707 | 0.82 | MEN1 (0.61) | — | |
| Morpholine SCHEMBL4757227 | 0.81 | MEN1 (0.46) | — | |
| Morpholine SCHEMBL22492177 | 0.81 | — | — | |
| Morpholine SCHEMBL3272572 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180186796-A1 | COMPOUNDS AND USES THEREOF | LEAD DISCOVERY SIENA S.R.L. (IT) | 2018-07-05 | — | — | US | disclosed |
| EP-3212649-A2 | COMPOUNDS AND USES THEREOF | Lead Discovery Siena S.r.l. (IT) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016066755-A2 | COMPOUNDS AND USES THEREOF | LEAD DISCOVERY SIENA S.R.L. (IT) | 2016-05-06 | — | — | WO | disclosed |
| EP-0577193-B1 | Photographic element comprising a combination of a development inhibiting releasing coupler and a bleach accelerator releasing compound | EASTMAN KODAK CO (US) | 1999-09-08 | — | — | EP | disclosed |
| EP-0577191-B1 | Photographic element and process comprising a bleach accelerator releasing compound and methods of making such compound | EASTMAN KODAK CO (US) | 1997-05-21 | — | — | EP | disclosed |
| EP-0577190-B1 | Photographic element comprising a bleach accelerator releasing compound containing an acid solubilizing group | EASTMAN KODAK CO (US) | 1997-05-21 | — | — | EP | disclosed |
| US-5358828-A | Coupler capable of forming wash-out dye | EASTMAN KODAK COMPANY (US) | 1994-10-25 | — | — | US | disclosed |
| US-5318879-A | Photographic element comprising a bleach accelerator releasing compound | EASTMAN KODAK COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| US-5300406-A | Coupler which forms dye that washes out during processing | EASTMAN KODAK COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| US-5286859-A | Bleach accelerating releasing coupler; forming chloroformate with phosgene, reacting with a thiol | EASTMAN KODAK COMPANY (US) | 1994-02-15 | — | — | US | disclosed |
| EP-0577190-A2 | Photographic element comprising a bleach accelerator releasing compound containing an acid solubilizing group | EASTMAN KODAK COMPANY (US) | 1994-01-05 | — | — | EP | disclosed |
| EP-0577193-A1 | Photographic element comprising a combination of a development inhibiting releasing coupler and a bleach accelerator releasing compound | EASTMAN KODAK COMPANY (US) | 1994-01-05 | — | — | EP | disclosed |
| EP-0577191-A2 | Photographic element and process comprising a bleach accelerator releasing compound and methods of making such compound | EASTMAN KODAK COMPANY (US) | 1994-01-05 | — | — | EP | disclosed |
| EP-0577192-A1 | Photographic element comprising a dir coupler and a barc coupler containing an acid solubilizing group | EASTMAN KODAK COMPANY (US) | 1994-01-05 | — | — | EP | disclosed |