Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7936118 | 1.00 | NPC1 (0.49) | NPC1RAB9ALMNAL3MBTL1TAAR1 | |
| SCHEMBL8415811 | 1.00 | NPC1 (0.49) | NPC1RAB9ALMNAL3MBTL1TAAR1 | |
| SCHEMBL10672855 | 0.86 | KDM4E (0.44) | NPC1RAB9ALMNAL3MBTL1TAAR1 | |
| SCHEMBL10672866 | 0.86 | KDM4E (0.44) | NPC1RAB9ALMNAL3MBTL1TAAR1 | |
| SCHEMBL10615869 | 0.85 | KMT2A (0.50) | NPC1RAB9ALMNAL3MBTL1TAAR1 | |
| SCHEMBL10615864 | 0.85 | KMT2A (0.50) | NPC1RAB9ALMNAL3MBTL1TAAR1 | |
| SCHEMBL11442570 | 0.80 | MAPT (0.51) | LMNAMEN1KMT2AG6PC1 | |
| SCHEMBL11307267 | 0.80 | MAPT (0.51) | LMNAMEN1KMT2AG6PC1 | |
| SCHEMBL8934289 | 0.79 | CYP1A2 (0.43) | NPC1RAB9ATAAR1MEN1KMT2A | |
| SCHEMBL7519004 | 0.79 | NPC1 (0.39) | NPC1RAB9ATAAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63264411-A | — | — | None | — | — | JP | disclosed |
| EP-0714885-B1 | Preparation process of aminoacetamide derivative | EISAI CO LTD (JP) | 1999-09-01 | — | — | EP | disclosed |
| EP-0714885-A2 | Preparation process of aminoacetamide derivative | EISAI CHEMICAL CO., LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |
| JP-S63264411-A | CARCINOSTATIC AGENT | RIKAGAKU KENKYUSHO | 1988-11-01 | — | — | JP | disclosed |
| US-4749792-A | Diamino ketones and alcohols as analgesic agents | E. R. SQUIBB & SONS, INC. (US) | 1988-06-07 | — | — | US | disclosed |