Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519008 | 1.00 | NPC1 (0.39) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL11467602 | 0.80 | ALDH1A1 (0.58) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL11467604 | 0.80 | ALDH1A1 (0.58) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL8934289 | 0.80 | CYP1A2 (0.43) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL7936118 | 0.79 | NPC1 (0.49) | NPC1RAB9AKMT2AMEN1TAAR1 | |
| SCHEMBL8415809 | 0.79 | NPC1 (0.49) | NPC1RAB9AKMT2AMEN1TAAR1 | |
| SCHEMBL8415811 | 0.79 | NPC1 (0.49) | NPC1RAB9AKMT2AMEN1TAAR1 | |
| SCHEMBL22340453 | 0.77 | CYP1A2 (0.47) | KMT2AALDH1A1MEN1TAAR1KDM4E | |
| SCHEMBL11221212 | 0.76 | MET (0.42) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL11221210 | 0.76 | MET (0.42) | NPC1RAB9AKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179529-A1 | NOVEL HYDROXAMIC ACID DERIVATIVES | Daiichi Fine Chemical Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-1101492-A1 | NOVEL REMEDIES FOR ALLERGIC DISEASES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |