SCHEMBL8415915

SCHEMBL8415915

CC(F)CCC[Si@H]1CC[C@H](CC[C@H]2CC[C@H](c3ccc(F)c(F)c3)CC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRIA4 P48058 1/20 0.32
USP30 Q70CQ3 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8415916 1.00 GRIA4 (0.32) GRIA4USP30ADRA1A
SCHEMBL8415942 0.87 GRIA4 (0.34) GRIA4USP30
SCHEMBL8415944 0.87 GRIA4 (0.34) GRIA4USP30
SCHEMBL7757728 0.85 CYP2C9 (0.35) USP30ADRA1A
SCHEMBL7757723 0.85 CYP2C9 (0.35) USP30ADRA1A
SCHEMBL7758770 0.85 CYP2C9 (0.35) USP30ADRA1A
SCHEMBL8415888 0.85 CYP2C9 (0.35) USP30ADRA1A
SCHEMBL7754844 0.83 CYP2C9 (0.37) GRIA4USP30
SCHEMBL7753093 0.83 CYP2C9 (0.37) GRIA4USP30
SCHEMBL7753091 0.83 CYP2C9 (0.37) GRIA4USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648773-B1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it SHINETSU CHEMICAL CO (JP) 1999-09-08 EP disclosed
US-5547606-A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-08-20 US disclosed
EP-0648773-A1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it Shin-Etsu Chemical Co., Ltd. (JP) 1995-04-19 EP disclosed