SCHEMBL8416013

SCHEMBL8416013

CCCCC[C@H]1CC[C@H](c2ccccc2-c2ccccc2[C@H]2CC[C@H](CCCCC)CC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NPC1 O15118 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
CYP2C19 P33261 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
OPRL1 P41146 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10882597 0.97 BCHE (0.41) BCHEACHEGAAMAPTMEN1
SCHEMBL9751895 0.91 GAA (0.41) GAAMAPTMEN1KMT2ANPC1
SCHEMBL29906122 0.91 GAA (0.41) GAAMAPTMEN1KMT2ANPC1
SCHEMBL262121 0.91 GAA (0.41) GAAMAPTMEN1KMT2ANPC1
SCHEMBL4650755 0.88 CYP2C9 (0.44) BCHEACHEMAPTMEN1KMT2A
SCHEMBL9639405 0.88 CYP2C9 (0.44) BCHEACHEMAPTMEN1KMT2A
SCHEMBL263717 0.86 PTGS2 (0.39) GAAMAPTMEN1KMT2ANPC1
SCHEMBL2035330 0.86 PTGS2 (0.39) GAAMAPTMEN1KMT2ANPC1
SCHEMBL224911 0.86 ESR2 (0.42) GAAMAPTCYP1A2CYP2C9HPGD
SCHEMBL262956 0.86 GAA (0.43) BCHEACHEGAAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6004479-A FLUOROETHERS FOR LIQUID CRYSTAL DISPLAYS AND DIELECTRICS MERCK KGAA (DE) 1999-12-21 US disclosed