SCHEMBL8416154

SCHEMBL8416154

CC(=O)OC(C)C(=O)Nc1c(I)c(CCC(=O)OCc2c(I)c(NC(=O)C(C)O)c(I)c(NC(=O)C(C)O)c2I)c(I)c(NC(=O)C(C)OC(C)=O)c1I

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8416155 0.82 LMNA (0.39) LMNA
SCHEMBL8416162 0.81
SCHEMBL7589131 0.81 HDAC3 (0.34) LMNA
SCHEMBL8416621 0.75 HDAC3 (0.31)
SCHEMBL8418058 0.70
SCHEMBL8416679 0.70
SCHEMBL10881983 0.70 LMNA (0.33) LMNA
SCHEMBL7591791 0.68
SCHEMBL10878285 0.68 HPGD (0.39) LMNA
SCHEMBL10877109 0.68 HPGD (0.39) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0782564-B1 IODINATED X-RAY CONTRAST MEDIA NYCOMED IMAGING AS (NO) 1999-09-01 EP disclosed