SCHEMBL8416192

SCHEMBL8416192

CCN(CC(=O)O)c1ccc(C=O)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 13/20 0.50
ALDH1A1 P00352 13/20 0.50
KDM4E B2RXH2 7/20 0.50
GAA P10253 5/20 0.49
HPGD P15428 2/20 0.49
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
LMNA P02545 4/20 0.49
HTT P42858 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
MAPK1 P28482 1/20 0.49
CRHBP P24387 1/20 0.49
CRHR2 Q13324 1/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
SMN1; SMN2 Q16637 5/20 0.47
ALOX12 P18054 1/20 0.47
BLM P54132 1/20 0.46
THRB P10828 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
RAB9A P51151 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56902 0.88 ALDH1A1 (0.61) MAPTALDH1A1KDM4EGAAHPGD
SCHEMBL29397257 0.88 ALDH1A1 (0.61) MAPTALDH1A1KDM4EGAAHPGD
Charcoal, Activated SCHEMBL31112505 0.86 ALDH1A1 (0.59) MAPTALDH1A1KDM4EGAAHPGD
Ammonia Solution, Strong SCHEMBL28913421 0.86 ALDH1A1 (0.59) MAPTALDH1A1KDM4EGAAHPGD
SCHEMBL10671772 0.85 ALDH1A1 (0.49) MAPTALDH1A1KDM4EGAAHPGD
Acrylic Acid SCHEMBL28390613 0.84 MAPT (0.52) MAPTALDH1A1KDM4EGAAHPGD
SCHEMBL20861924 0.83 ALDH1A1 (0.53) MAPTALDH1A1KDM4EGAAHPGD
Hydrazine SCHEMBL28805662 0.83 ALDH1A1 (0.57) MAPTALDH1A1KDM4EGAAHPGD
SCHEMBL1941048 0.81 MAPT (0.44) MAPTALDH1A1KDM4EGAAHPGD
SCHEMBL61553 0.81 ALDH1A1 (0.50) MAPTALDH1A1KDM4EGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0565074-B1 Process for the preparation of binary sensitizing dyes EASTMAN KODAK CO (US) 1999-08-25 EP disclosed
US-5756740-A Process for the preparation of binary sensitizing dyes EASTMAN KODAK COMPANY (US) 1998-05-26 US disclosed
EP-0565074-A2 Process for the preparation of binary sensitizing dyes EASTMAN KODAK COMPANY (US) 1993-10-13 EP disclosed