Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 11/20 | 0.65 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.51 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8418205 | 0.81 | KCNH2 (0.62) | KCNH2METTL3METTL14 | |
| SCHEMBL8415553 | 0.81 | KCNH2 (0.62) | KCNH2METTL3METTL14 | |
| Maleic Acid SCHEMBL8418202 | 0.81 | KCNH2 (0.62) | KCNH2METTL3METTL14 | |
| SCHEMBL8119266 | 0.80 | KCNH2 (0.70) | KCNH2METTL3METTL14 | |
| SCHEMBL11834266 | 0.78 | KCNH2 (0.74) | KCNH2 | |
| SCHEMBL8112807 | 0.77 | KCNH2 (0.73) | KCNH2 | |
| Maleic Acid SCHEMBL8418382 | 0.75 | KCNH2 (0.64) | KCNH2METTL3METTL14 | |
| Fumaric Acid SCHEMBL8418386 | 0.75 | KCNH2 (0.64) | KCNH2METTL3METTL14 | |
| SCHEMBL8415269 | 0.75 | KCNH2 (0.59) | KCNH2METTL3METTL14 | |
| Hydrochloric Acid SCHEMBL8416468 | 0.75 | KCNH2 (0.72) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939077-A2 | 3-Substituted 1-arylindole compounds as 5-HT2 antagonists | H. LUNDBECK A/S (DK) | 1999-09-01 | — | — | EP | disclosed |
| EP-0734384-A1 | 3-SUBSTITUTED 1-ARYLINDOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016684-A1 | 3-SUBSTITUTED 1-ARYLINDOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 1995-06-22 | — | — | WO | disclosed |