Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33457 | 0.98 | — | — | |
| SCHEMBL29619673 | 0.98 | — | — | |
| SCHEMBL19560102 | 0.98 | — | — | |
| SCHEMBL2383959 | 0.98 | LMNA (0.50) | LMNAMEN1KMT2AKDM4EDUSP3 | |
| SCHEMBL28286833 | 0.95 | LMNA (0.48) | LMNAMEN1KMT2AKDM4EDUSP3 | |
| SCHEMBL28113653 | 0.95 | LMNA (0.48) | LMNAMEN1KMT2AKDM4EDUSP3 | |
| SCHEMBL29000916 | 0.95 | LMNA (0.48) | LMNAMEN1KMT2AKDM4EDUSP3 | |
| SCHEMBL29159555 | 0.95 | LMNA (0.48) | LMNAMEN1KMT2AKDM4EDUSP3 | |
| SCHEMBL27802308 | 0.95 | LMNA (0.48) | LMNAMEN1KMT2AKDM4EDUSP3 | |
| SCHEMBL8638257 | 0.95 | LMNA (0.48) | LMNAMEN1KMT2AKDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941323-A1 | BONE MORPHOGENETIC PROTEIN-16 (BMP-16) COMPOSITIONS | GENETICS INSTITUTE, INC. (US) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998012322-A1 | BONE MORPHOGENETIC PROTEIN-16 (BMP-16) COMPOSITIONS | GENETICS INSTITUTE, INC. (US) | 1998-03-26 | — | — | WO | disclosed |