SCHEMBL8416615

SCHEMBL8416615

CCCOC(=O)/C=C\C(=O)OC(O)CC

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.58
ATM Q13315 1/20 0.52
MAPT P10636 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
APP P05067 3/20 0.40
ALOX5 P09917 1/20 0.39
TSHR P16473 3/20 0.36
HPGD P15428 1/20 0.36
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8416622 1.00 HCAR2 (0.58) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9188811 0.89 ATM (0.69) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9188802 0.89 ATM (0.69) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL8419555 0.86 HCAR2 (0.63) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL8419548 0.86 HCAR2 (0.63) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL950768 0.86 TSHR (0.43) HCAR2ATMTSHR
SCHEMBL301455 0.86 TSHR (0.43) HCAR2ATMTSHR
SCHEMBL301454 0.86 TSHR (0.43) HCAR2ATMTSHR
SCHEMBL8416554 0.85 HCAR2 (0.55) HCAR2ATMMAPTNPSR1TSHR
SCHEMBL8416560 0.85 HCAR2 (0.55) HCAR2ATMMAPTNPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001892-A (A) UNSATURATED POLYESTER; (B) VINYL ETHER COMPONENT OF GIVEN FORMULA; AND (C) REACTIVE DILUENT COMPRISING AN UNSATURATED DIOIC ESTER OF GIVEN FORMULA, THE DILUENT LOWERS THE INITIAL APPLICATION VISCOSITY WITHOUT INCREASING CURE TIME PPG INDUSTRIES OHO, INC. (US) 1999-12-14 US disclosed
EP-0771331-B1 POLYESTER AND VINYL ETHER RADIATION CURABLE COMPOSITIONS WITH REACTIVE DILUENT PPG INDUSTRIES INC (US) 1998-08-26 EP disclosed
EP-0771331-A1 POLYESTER AND VINYL ETHER RADIATION CURABLE COMPOSITIONS WITH REACTIVE DILUENT PPG INDUSTRIES, INC. (US) 1997-05-07 EP disclosed
WO-1996001283-A1 POLYESTER AND VINYL ETHER RADIATION CURABLE COMPOSITIONS WITH REACTIVE DILUENT PPG INDUSTRIES, INC. (US) 1996-01-18 WO disclosed