SCHEMBL8416730

SCHEMBL8416730

O=C1C(c2ccccc2)=CC(c2ccccc2)=C1c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 5/20 0.61
PDE4B Q07343 2/20 0.50
PTPN1 P18031 3/20 0.48
PTPRC P08575 2/20 0.48
CDC25B P30305 2/20 0.48
PTPRF P10586 1/20 0.48
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
HSD17B3 P37058 1/20 0.44
P2RX7 Q99572 1/20 0.38
FGFR1 P11362 1/20 0.37
FGFR2 P21802 1/20 0.37
FGFR4 P22455 1/20 0.37
FGFR3 P22607 1/20 0.37
MITF O75030 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28365226 1.00 BACE1 (0.61) BACE1PDE4BPTPN1PTPRCCDC25B
SCHEMBL28351879 0.91 BACE1 (0.52) BACE1PDE4BPTPN1PTPRCCDC25B
Diphenylether SCHEMBL27545344 0.89 BACE1 (0.50) BACE1PDE4BPTPN1PTPRCCDC25B
SCHEMBL28588426 0.89 MGAM (0.53) BACE1PDE4BPTPN1PTPRCCDC25B
SCHEMBL29013073 0.86 BACE1 (0.71) BACE1PDE4BPTPN1FGFR1FGFR2
SCHEMBL7865883 0.86 BACE1 (0.71) BACE1PDE4BPTPN1FGFR1FGFR2
SCHEMBL13569206 0.86 BACE1 (0.47) BACE1PDE4BPTPN1PTPRCCDC25B
SCHEMBL30034971 0.86 BACE1 (0.47) BACE1PDE4BPTPN1PTPRCCDC25B
SCHEMBL14094765 0.86 BACE1 (0.47) BACE1PDE4BPTPN1PTPRCCDC25B
SCHEMBL28093190 0.82 BACE1 (0.47) BACE1PDE4BPTPN1PTPRCCDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105255237-B Interior wall building heat preservation heat-barrier material 重庆硕奥科技有限公司 2017-10-31 CN claimed
CN-105255237-A Building insulating material for inner wall UNIV CHONGQING RADIO & TV 2016-01-20 CN claimed
CN-105176316-A Thermal-insulation paint for building external walls UNIV CHONGQING RADIO & TV 2015-12-23 CN claimed
CN-101100420-B Method for synthesizing 3,3'-(p-phenyleneoxy)di(2,4,5-triphenyl)cyclopentadiene CHINESE ACAD INST CHEMISTRY 2010-12-29 CN claimed
CN-100575385-C Compositions and methods for obtaining polyarylene networks with reduced thermal expansion DOW GLOBAL TECHNOLOGIES INC 2009-12-30 CN claimed
CN-1745120-A Composition and method to achieve reduced thermal expansion in polyarylene networks DOW GLOBAL TECHNOLOGIES INC (US) 2006-03-08 CN claimed
CN-1210362-C Adhesion promoter and self-priming resin compositions and articles made therefrom DOW GLOBAL TECHNOLOGIES INC (US) 2005-07-13 CN claimed
CN-1318093-A Adhesion promoter and self-priming resin compositions and articles made therefrom DOW CHEMICAL CO (US) 2001-10-17 CN claimed
US-20250313975-A1 SULFUR DIOXIDE DEPOLARIZED ELECTROLYZER AND METHOD FOR PERFORMANCE RECOVERY Peregrine Hydrogen Inc. (US) 2025-10-09 US disclosed
US-20250297372-A1 SULFUR DIOXIDE ELECTROLYZER WITH IMPROVED SULFURIC ACID CONCENTRATION FORMATION AND METHOD OF OPERATION Peregrine Hydrogen Inc. (US) 2025-09-25 US disclosed
US-12084554-B2 Polyphenylenes, methods, and uses thereof SIMON FRASER UNIVERSITY (CA) 2024-09-10 US disclosed
US-11970590-B2 Polyphenylenes, methods, and uses thereof SIMON FRASER UNIVERSITY 2024-04-30 US disclosed
US-20240117132-A1 POLYPHENYLENES, METHODS, AND USES THEREOF SIMON FRASER UNIVERSITY (CA) 2024-04-11 US disclosed
US-11802187-B2 Polyphenylenes, methods, and uses thereof SIMON FRASER UNIVERSITY (CA) 2023-10-31 US disclosed
CN-1745120-A Composition and method to achieve reduced thermal expansion in polyarylene networks DOW GLOBAL TECHNOLOGIES INC (US) 2006-03-08 CN disclosed
CN-1210362-C Adhesion promoter and self-priming resin compositions and articles made therefrom DOW GLOBAL TECHNOLOGIES INC (US) 2005-07-13 CN disclosed
CN-1443211-A Spin-on dielectric composition with coating enhancer DOW WORLDWIDE TECHNOLOGY CO (US) 2003-09-17 CN disclosed
CN-1328589-A Composition containing cross-linkable matrix precursor and poragen, and porous matrix prepared therefrom DOW CHEMICAL CO (US) 2001-12-26 CN disclosed
CN-1318093-A Adhesion promoter and self-priming resin compositions and articles made therefrom DOW CHEMICAL CO (US) 2001-10-17 CN disclosed
US-5965679-A BASED A BISCYCLOPENTADIENONE AND AN AROMATIC DIACETYLENE; CURING; LOW DIELECTRIC; INTEGRATED CIRCUITS; MICROELECTRONICS; PRINTED CIRCUITS THE DOW CHEMICAL COMPANY (US) 1999-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240117132-A1 POLYPHENYLENES, METHODS, AND USES THEREOF PICALM, PARN, PHOSPHO1 BACE1 4238/4885PDE4B 4291/4885PTPN1 2343/4885
US-11802187-B2 Polyphenylenes, methods, and uses thereof PICALM, PARN, PHOSPHO1 BACE1 4316/4885PDE4B 4017/4885PTPN1 2727/4885
US-12084554-B2 Polyphenylenes, methods, and uses thereof PICALM, PARN, PHOSPHO1 BACE1 4238/4885PDE4B 4291/4885PTPN1 2343/4885
US-11970590-B2 Polyphenylenes, methods, and uses thereof PICALM, PARN, PHOSPHO1 BACE1 4238/4885PDE4B 4291/4885PTPN1 2343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.