Phosphine

Phosphine

SCHEMBL8416873

OCCc1ccccc1Br.P

nearest known ligand 0.58

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.58
IDO1 P14902 2/20 0.45
GPR52 Q9Y2T5 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
TSHR P16473 1/20 0.38
CYP2A13 Q16696 1/20 0.37
ALDH1A1 P00352 2/20 0.37
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
PYCR1 P32322 1/20 0.36
KMT2A Q03164 1/20 0.36
RIPK1 Q13546 1/20 0.36
PARP10 Q53GL7 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29590438 0.98 TAAR1 (0.60) TAAR1IDO1GPR52TDP1TSHR
SCHEMBL286557 0.98 TAAR1 (0.60) TAAR1IDO1GPR52TDP1TSHR
SCHEMBL4119364 0.86 TAAR1 (0.48) TAAR1IDO1GPR52TDP1TSHR
SCHEMBL534245 0.84 TAAR1 (0.56) TAAR1IDO1GPR52TSHRCYP2A13
SCHEMBL30769022 0.84 TAAR1 (0.56) TAAR1IDO1GPR52TSHRCYP2A13
SCHEMBL3028718 0.82 TAAR1 (0.54) TAAR1IDO1GPR52TSHRALDH1A1
SCHEMBL6738136 0.82 TAAR1 (0.71) TAAR1IDO1GPR52TSHRCYP2A13
SCHEMBL29351396 0.82 TAAR1 (0.71) TAAR1IDO1GPR52TSHRCYP2A13
SCHEMBL9026542 0.80 TAAR1 (0.52) TAAR1IDO1GPR52TSHRALDH1A1
SCHEMBL22288310 0.79 TAAR1 (0.40) TAAR1IDO1GPR52TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5958906-A Phospholipid derivatives containing higher elements of the fifth main group ASTA-MEDICA AKTIENGESELLSCHAFT (DE) 1999-09-28 US disclosed